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Delivering Growth Factors through a Polymeric Scaffold to Cell Cultures Containing both Nucleus Pulposus and Annulus Fibrosus
(Turk Neurosurg, 2018-04-24)
AIM: To design a novel, polyvinyl alcohol (PVA)-based polymeric scaffold that permits the controlled release of insulin-like growth
factor 1 (IGF-1)/bone morphogenetic protein (BMP)-2 following intervertebral disc ...
Investigation of the effect of dipyrone on cells isolated from intervertebral disc tissue
(Experimental and Therapeutic Medicine, 2019-02-28)
The present study aimed to evaluate the effects of dipyrone, an indispensable analgesic, anti-pyretic and anti-spasmodic used in emergency departments, on nucleus pulposus and annulus fibrosus cells invitro. ...
Effects of etanercept, a tumor necrosis factor receptor fusion protein, on primary cell cultures prepared from intact human intervertebral disc tissue
(Experimental and Therapeutic Medicine, 2019-02-06)
The aim of the present study was to investigate the effects of etanercept (ETA), a tumor necrosis factor (TNF) inhibitor, on human cell cultures prepared from intact intervertebral disc tissue. ETA is used as a treatment ...
Are Specific Gene Expressions of Extracellular Matrix and Nucleus Pulposus Affected by Primary Cell Cultures Prepared from Intact or Degenerative Intervertebral Disc Tissues?
(Turk Neurosurg, 2018-02-26)
AIM: To determine the gene expression patterns of nucleus pulposus (NP) in cell cultures obtained from degenerated or intact
tissues.
MATERIAL and METHODS: Whereas 12 of the cases were diagnosed with lumbar disc herniation ...
A Rare and Unusual Complication of Kyphoplasty: A Case Report of Spinal Subdural Hemotoma
(Journal of Academic Research in Medicine, 2019)
For vertebral fractures, kyphoplasty appears to be the most innocent treatment modality, but percutaneous injection of kyphoplasty cement might
cause serious complications as the injection causes increased venous pressure ...
Pregabalin treatment for neuropathic pain may damage intervertebral disc tissue
(Experimental and Therapeutic Medicine, 2018-03-23)
The aim of the present study was to determine whether pharmaceutical preparations with pregabalin (PGB) as an active ingredient, which are widely prescribed by clini-cians, exert toxic effects on human primary ...
The association between different molecular weights of hyaluronic acid and CHAD, HIF-1α, COL2A1 expression in chondrocyte cultures
(Experimental and Therapeutic Medicine, 2018-01)
The aim of the present study was to investigate the effects of three different formulations of hyaluronic acid (HA): Low molecular weight (MW) Sinovial One®, medium MW Viscoplus® and high MW Durolane®, on chondrocyte ...
Are radio‐contrast agents commonly used in discography toxicto the intact intervertebral disc tissue cells?
(Basic Clinical Pharmacology Toxicology, 2018-08-13)
In the literature, there have been no studies showing clear results on how radio‐contrast pharmaceuticals would affect intact disc tissue cells. In this context, itwas aimed to evaluate the effects of iopromide and gadoxetic ...
Anterior Servikal Diskektomi Hastalarında Füzyon Sonuçlarının Radyolojik ve Klinik Olarak Karşılaştırılması
(Journal of Academic Research in Medicine, 2019-03-19)
Amaç: Bu çalışmada anterior servikal mikrodiskektomi cerrahisinde füzyon yapılan ve
yapılmayan hastaların klinik ve radyolojik takip ve sonuçlarını birbirleri ile karşılaştırılarak
füzyonlu anterior servikal mikrodiskektominin ...
Will it be possible to prevent lumbar degenerative disc diseases in the future by means of vitamin D receptor gene manipulation?
(Merit Research Journal of Medicine and Medical Sciences, 2017-10)
It is primarily aimed to study polymorphisms in vitamin D receptor gene (VDR), which is one of the genetic
factors having a role in the formation of lumbar pathologies and/or causing higher incidence of pathologic
processes. ...