Search
Now showing items 1-10 of 12
Investigation of the effect of dipyrone on cells isolated from intervertebral disc tissue
(Experimental and Therapeutic Medicine, 2019-02-28)
The present study aimed to evaluate the effects of dipyrone, an indispensable analgesic, anti-pyretic and anti-spasmodic used in emergency departments, on nucleus pulposus and annulus fibrosus cells invitro. ...
Effects of etanercept, a tumor necrosis factor receptor fusion protein, on primary cell cultures prepared from intact human intervertebral disc tissue
(Experimental and Therapeutic Medicine, 2019-02-06)
The aim of the present study was to investigate the effects of etanercept (ETA), a tumor necrosis factor (TNF) inhibitor, on human cell cultures prepared from intact intervertebral disc tissue. ETA is used as a treatment ...
Does Nimodipine, a Selective Calcium Channel Blocker, Impair Chondro-cyte Proliferation or Damage Extracellular Matrix Structures?
(Current Pharmaceutical Biotechnology, 2019-04-17)
Background:
The study aimed to investigate the effects of the active ingredient, nimodipine, on chondrocyte proliferation and extracellular matrix (ECM) structures in cartilage tissue cells.
Methods:
Chondrocyte ...
Investigation of the Effects of Methylphenidate, an Amphetamine Derivative, on Intervertebral Disc Tissue Cell Cultures and Matrix Structures
(Turk Neurosurg, 2019-07-24)
AIM: To investigate the effects of methylphenidate (MPH), on intervertebral disc tissue (IVD) cell cultures and extracellular matrix
structures. Changes in the expression of some important marker genes involved in anabolic ...
Which pharmacological agents may be used to establish healthy, proliferating human primer nucleus pulposus / annulus fibrosus cell cultures? Systematic evaluation of our experience in the light of literature
(Merit Research Journal of Medicine and Medical Sciences, 2018-03)
Intervertebral disc tissue is damaged and loses its normal physiological
functions due to age-related degeneration, vigorous physical activity and
trauma in all age groups and at any stage of life. Here we aim to present ...
Pregabalin treatment for neuropathic pain may damage intervertebral disc tissue
(Experimental and Therapeutic Medicine, 2018-03-23)
The aim of the present study was to determine whether pharmaceutical preparations with pregabalin (PGB) as an active ingredient, which are widely prescribed by clini-cians, exert toxic effects on human primary ...
The association between different molecular weights of hyaluronic acid and CHAD, HIF-1α, COL2A1 expression in chondrocyte cultures
(Experimental and Therapeutic Medicine, 2018-01)
The aim of the present study was to investigate the effects of three different formulations of hyaluronic acid (HA): Low molecular weight (MW) Sinovial One®, medium MW Viscoplus® and high MW Durolane®, on chondrocyte ...
Will it be possible to prevent lumbar degenerative disc diseases in the future by means of vitamin D receptor gene manipulation?
(Merit Research Journal of Medicine and Medical Sciences, 2017-10)
It is primarily aimed to study polymorphisms in vitamin D receptor gene (VDR), which is one of the genetic
factors having a role in the formation of lumbar pathologies and/or causing higher incidence of pathologic
processes. ...
Does transcription factor, induced by daptomycin and vancomycin, affect HIF-1α, Chondroadherin, and COL2A1?
(Annals of Medical Research, 2018)
Aim: In this study, it was firstly aimed to investigate the effect of Daptomycin (DAP) on the proliferation in Vancomycin (VCM)-
administered primary chondrocyte cultures and non-drug-administered primary chondrocyte ...
Investigation of the effect of dipyrone on cells isolated from intervertebral disc tissue
(Experimental And Therapeutic Medicine, 2019)
The present study aimed to evaluate the effects of dipyrone, an indispensable analgesic, anti‑pyretic and anti‑spasmodic used in emergency departments, on nucleus pulposus and annulus fibrosus cells in vitro. After surgical ...