Search
Now showing items 1-5 of 5
Effects of etanercept, a tumor necrosis factor receptor fusion protein, on primary cell cultures prepared from intact human intervertebral disc tissue
(Experimental and Therapeutic Medicine, 2019-02-06)
The aim of the present study was to investigate the effects of etanercept (ETA), a tumor necrosis factor (TNF) inhibitor, on human cell cultures prepared from intact intervertebral disc tissue. ETA is used as a treatment ...
Does Nimodipine, a Selective Calcium Channel Blocker, Impair Chondro-cyte Proliferation or Damage Extracellular Matrix Structures?
(Current Pharmaceutical Biotechnology, 2019-04-17)
Background:
The study aimed to investigate the effects of the active ingredient, nimodipine, on chondrocyte proliferation and extracellular matrix (ECM) structures in cartilage tissue cells.
Methods:
Chondrocyte ...
Investigation of the Effects of Methylphenidate, an Amphetamine Derivative, on Intervertebral Disc Tissue Cell Cultures and Matrix Structures
(Turk Neurosurg, 2019-07-24)
AIM: To investigate the effects of methylphenidate (MPH), on intervertebral disc tissue (IVD) cell cultures and extracellular matrix
structures. Changes in the expression of some important marker genes involved in anabolic ...
Pregabalin treatment for neuropathic pain may damage intervertebral disc tissue
(Experimental and Therapeutic Medicine, 2018-03-23)
The aim of the present study was to determine whether pharmaceutical preparations with pregabalin (PGB) as an active ingredient, which are widely prescribed by clini-cians, exert toxic effects on human primary ...
The association between different molecular weights of hyaluronic acid and CHAD, HIF-1α, COL2A1 expression in chondrocyte cultures
(Experimental and Therapeutic Medicine, 2018-01)
The aim of the present study was to investigate the effects of three different formulations of hyaluronic acid (HA): Low molecular weight (MW) Sinovial One®, medium MW Viscoplus® and high MW Durolane®, on chondrocyte ...