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Delivering Growth Factors through a Polymeric Scaffold to Cell Cultures Containing both Nucleus Pulposus and Annulus Fibrosus
(Turk Neurosurg, 2018-04-24)
AIM: To design a novel, polyvinyl alcohol (PVA)-based polymeric scaffold that permits the controlled release of insulin-like growth
factor 1 (IGF-1)/bone morphogenetic protein (BMP)-2 following intervertebral disc ...
Investigation of the effect of dipyrone on cells isolated from intervertebral disc tissue
(Experimental and Therapeutic Medicine, 2019-02-28)
The present study aimed to evaluate the effects of dipyrone, an indispensable analgesic, anti-pyretic and anti-spasmodic used in emergency departments, on nucleus pulposus and annulus fibrosus cells invitro. ...
Effects of etanercept, a tumor necrosis factor receptor fusion protein, on primary cell cultures prepared from intact human intervertebral disc tissue
(Experimental and Therapeutic Medicine, 2019-02-06)
The aim of the present study was to investigate the effects of etanercept (ETA), a tumor necrosis factor (TNF) inhibitor, on human cell cultures prepared from intact intervertebral disc tissue. ETA is used as a treatment ...
Pregabalin treatment for neuropathic pain may damage intervertebral disc tissue
(Experimental and Therapeutic Medicine, 2018-03-23)
The aim of the present study was to determine whether pharmaceutical preparations with pregabalin (PGB) as an active ingredient, which are widely prescribed by clini-cians, exert toxic effects on human primary ...
Are radio‐contrast agents commonly used in discography toxicto the intact intervertebral disc tissue cells?
(Basic Clinical Pharmacology Toxicology, 2018-08-13)
In the literature, there have been no studies showing clear results on how radio‐contrast pharmaceuticals would affect intact disc tissue cells. In this context, itwas aimed to evaluate the effects of iopromide and gadoxetic ...
Investigation of the effect of dipyrone on cells isolated from intervertebral disc tissue
(Experimental And Therapeutic Medicine, 2019)
The present study aimed to evaluate the effects of dipyrone, an indispensable analgesic, anti‑pyretic and anti‑spasmodic used in emergency departments, on nucleus pulposus and annulus fibrosus cells in vitro. After surgical ...